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2011 Pigment Cell Melanoma Res 24(2): 326-333 ... [0] A proliferative melanoma cell phenotype is responsive to RAF/MEK inhibition independent of BRAF mutation status Zipser MC, Eichhoff OM, Widmer DS, Schlegel NC, Schoenewolf NL, Stuart D, Liu W, Gardner H, Smith PD, Nuciforo P, Dummer R, Hoek KS |
2010 J Natl Cancer Inst 102(15): 1148-1159 ... [3] GLI2-mediated melanoma invasion and metastasis Alexaki VI, Javelaud D, Van Kempen LC, Mohammad KS, Dennler S, Luciani F, Hoek KS, Juarez P, Goydos JS, Fournier PJ, Sibon C, Bertolotto C, Verrecchia F, Saule S, Delmas V, Ballotti R, Larue L, Saiag P, Guise TA, Mauviel A |
2010 Melanoma Res 20(4): 349-355 ... [1] The immunohistochemistry of invasive and proliferative phenotype switching in melanoma: a case report Eichhoff OM, Zipser MC, Xu M, Weeraratna AT, Mihic D, Dummer R, Hoek KS |
2009 Oncogene 28(47): 4147-4161 ... [3] Loss of pigment epithelium-derived factor enables migration, invasion and metastatic spread of human melanoma Orgaz JL, Ladhani O, Hoek KS, Fernandez-Barral A, Mihic D, Aguilera O, Seftor EA, Bernad A, Rodreguez-Peralto JL, Hendrix MJ, Volpert OV, Jiminez B |
2009 J Biol Chem 284(42): 28704-28712 ... [8] Heparan sulfate proteoglycan modulation of Wnt5A signal transduction in metastatic melanoma cells OConnell MP, Fiori JL, Kershner EK, Frank BP, Indig FE, Taub DD, Hoek KS, Weeraratna AT |
2009 P Natl Acad Sci USA 22(4): 445-453 ... [5] CT-X antigen expression in human breast cancer Grigoriadis A, Caballero OL, Hoek KS, da Silva L, Chen YT, Shin SJ, Jungbluth AA, Miller LD, Clouston D, Cebon J, Old LJ, Lakhani SR, Simpson AJ, Neville AM |
2009 Pigment Cell Melanoma Res 22(4): 445-453 ... [3] Id2 suppression of p15 counters TGF-beta-mediated growth inhibition of melanoma cells Schlegel NC, Eichhoff OM, Hemmi S, Werner S, Dummer R, Hoek KS |
2009 Clin Cancer Res 15(6): 1954-1963 ... [3] Sperm-derived SPANX-B is a clinically relevant tumor antigen that is expressed in human tumors and readily recognized by human CD4 and CD8 T cells Almanzar G, Olkhanud PB, Bodogai M, Dellagnola C, Baatar D, Hewitt SM, Ghimenton C, Tummala MK, Weeraratna AT, Hoek KS, Kouprina N, Larionov V, Biragyn A |
2009 BMC Cancer 9: 52 ... [2] Loss of full length CtBP1 expression enhances the invasive potential of human melanoma Winklmeier A, Poser I, Hoek KS, Bosserhoff AK |
2009 Endocrinology 150(6): 2551-2560 ... [4] Filamin A modulates kinase activation and intracellular trafficking of epidermal growth factor receptors in human melanoma cells Fiori JL, Zhu TN, OConnell MP, Hoek KS, Indig FE, Frank BP, Morris C, Kole S, Hasskamp J, Elias G, Weeraratna AT, Bernier M |
2009 J Invest Dermatology 129(7): 1782-1789 ... [9] Wnt5A activates the calpain-mediated cleavage of filamin A OConnell MP, Fiori JL, Baugher KM, Indig FE, French AD, Camilli TC, Frank BP, Earley R, Hoek KS, Hasskamp JH, Elias EG, Taub DD, Bernier M, Weeraratna AT |
2009 Exp Dermatol 18(1): 69-77 ... [6] Green tea extract reduces induction of p53 and apoptosis in UVB-irradiated human skin independent of transcriptional controls Mnich CD, Hoek KS, Virkki LV, Farkas A, Dudli C, Laine E, Urosevic M, Dummer R |
2008 Cancer Res 68(24): 10205-10214 ... [18] Wnt5A regulates expression of tumor-associated antigens in melanoma via changes in signal transducers and activators of transcription 3 phosphorylation Dissanayake SK, Olkhanud PB, OConnell MP, Carter A, French AD, Camilli TC, Emeche CD, Hewitt KJ, Rosenthal DT, Leotlela PD, Wade MS, Yang SW, Brant L, Nickoloff BJ, Messina JL, Biragyn A, Hoek KS, Taub DD, Longo DL, Sondak VK, Hewitt SM, Weeraratna AT |
2008 Pigment Cell Melanoma Res 21(6): 665-676 ... [16] Novel MITF targets identified using a two-step DNA microarray strategy Hoek KS, Schlegel NC, Eichhoff OM, Widmer DS, Praetorius C, Einarsson SO, Valgeirsdottir S, Bergsteinsdottir K, Schepsky A, Dummer R, Steingrimsson E |
2008 Cancer Res 68(3): 650-656 ... [40] In vivo switching of human melanoma cells between proliferative and invasive states Hoek KS, Eichhoff OM, Schlegel NC, Döbbeling U, Kobert N, Schaerer L, Hemmi S, Dummer R |
2007 Melanoma Res 17(2): 131-136 ... [1] Reduced pSmad2 immunodetection correlates with increased primary melanoma thickness Mnich CD, Hoek KS, Oberholzer PA, Seifert B, Hafner J, Dummer R, Mihic D |
2007 Pigment Cell Res 20(2): 112-119 ... [15] Loss of maspin expression contributes to a more invasive potential in malignant melanoma Denk AE, Bettstetter M, Wild PJ, Hoek K, Bataille F, Dietmaier W, Bosserhoff AK |
2006 Gene Dev 20(24): 3426-3439 ... [78] Mitf regulation of Dia1 controls melanoma proliferation and invasiveness Carreira S, Goodall J, Denat L, Rodriguez M, Nuciforo P, Hoek KS, Testori A, Larue L, Goding CR |
2006 Pigment Cell Res 19(4): 290-302 ... [86] Metastatic potential of melanomas defined by specific gene expression profiles with no BRAF signature Hoek KS, Schlegel NC, Brafford P, Sucker A, Ugurel S, Kumar R, Weber BL, Nathanson KL, Phillips DJ, Herlyn M, Schadendorf D, Dummer R |
2005 Cancer Biol Ther 41(9): 1018-1029 ... [38] Whole-genome expression profiling of the melanoma progression pathway reveals marked molecular differences between nevi/melanoma in situ and advanced-stage melanomas Smith AP, Hoek K, Becker D |
2004 Cancer Res 64(15): 5270-5282 ... [185] Expression profiling reveals novel pathways in the transformation of melanocytes to melanomas Hoek K, Rimm DL, Williams KR, Zhao H, Ariyan S, Lin A, Kluger HM, Berger AJ, Cheng E, Trombetta ES, Wu T, Niinobe M, Yoshikawa K, Hannigan GE, Halaban R |
2002 J Biol Chem 277(20): 18010-18020 ... [47] Heterogeneous nuclear ribonucleoprotein A3, a novel RNA trafficking response element-binding protein Ma AS, Moran-Jones K, Shan J, Munro TP, Snee MJ, Hoek KS, Smith R |
2000 J Biol Chem 275(49): 38286-38295 ... [29] Binding of an RNA trafficking response element to heterogeneous nuclear ribonucleoproteins A1 and A2 Shan J, Moran-Jones K, Munro TP, Kidd GJ, Winzor DJ, Hoek KS, Smith R |
1998 Biochemistry 37(19): 7021-7029 ... [128] hnRNP A2 selectively binds the cytoplasmic transport sequence of myelin basic protein mRNA Hoek KS, Kidd GJ, Carson JH, Smith R |
1997 Antimicrob Agents Chemother 41(1): 54-59 ... [69] Antibacterial activity of bovine lactoferrin-derived peptides Hoek KS, Milne JM, Grieve PA, Dionysius DA, Smith R |
1993 J Food Sci 58(4): 780-784 ... [8] Trypsin-like enzyme from sand crab (Portunus pelagicus): purification and characterization Dionysius DA, Hoek KS, Milne JM, Slattery SL |